Optimizing pharmaceutical processes with precision dosing pumps
Precision in pharmaceutical dosing: an absolute necessity
The pharmaceutical industry requires precision and reliability standards that go well beyond those of any other industrial sector. Nova Rotors dosing pumps are specifically designed to guarantee repeatable accuracy even with complex fluids, integrating advanced control technologies, certified calibration systems and validation protocols compliant with GMP regulations.
While they share some characteristics with sanitary pumps, those for pharmaceutical use are generally more focused on industrial applications and production, but must still meet very high quality, precision and safety requirements.
In the pharmaceutical sector, every milliliter counts. Dosing precision is not just a matter of product quality, but represents a fundamental regulatory requirement that guarantees therapeutic efficacy and patient safety. Nova Rotors screw volumetric pumps for the pharmaceutical sector have been developed to respond to this critical need.
Dosing pumps: challenges in pharmaceutical dosing
The pharmaceutical industry presents unique challenges that require specialized solutions:
- Dosing of active ingredients in extremely precise concentrations
- Handling fluids with variable viscosities and complex rheological properties
- Maintaining sterility throughout the entire process
- Complete traceability of every batch produced
- Compliance with FDA, EMA and GMP regulations
Integrable control technologies for maximum precision
Nova Rotors screw volumetric pumps integrate advanced control systems that guarantee dosing precision superior to 99.5% even in the most demanding operating conditions.
Electronic control systems
Nova Rotors control systems offer:
- Variable speed control: High-resolution frequency inverters for fine flow rate regulation
- Real-time monitoring: Pressure, temperature and flow sensors on demand integrated in the system
- Digital interfaces: Modbus, Profibus and Ethernet/IP communication protocols for integration with SCADA systems
Closed feedback loop
The closed-loop control system allows automatic real-time corrections, compensating for variations in:
- Fluid viscosity
- Process temperature
- System pressure
- Normal component wear
HTS series: excellence for pharmaceutical applications
The Raptor HTS (Hygienic Twin Screw) series represents the state of the art in hygienic twin screw pump technology for the pharmaceutical sector. Designed to achieve the maximum level of hygiene and precision, these pumps offer unique characteristics:
Certified hygienic design
- Completely smooth surfaces without dead zones
- Parts in contact with the product are all in stainless steel
- Almost total absence of rubber parts in contact with the product
- Standard tri-clamp sanitary connections
- 3-A Sanitary Standards certification
- FDA compliance and regulation 1935/2004
Certified pharmaceutical materials
HTS pumps use exclusively certified materials for pharmaceutical use:
- 316L stainless steel: superior chemical resistance and electropolished finish
- USP Class VI elastomers: pharmaceutical silicone and FKM (Viton®) for aggressive applications
- Certified seals: O-rings and seals compliant with the most stringent pharmaceutical regulations
MX single-screw metering pumps for various pharmaceutical applications
Active ingredient dosing
For dosing API (Active Pharmaceutical Ingredients), Nova Rotors offers pumps with precision up to ±0.1% of the nominal value, guaranteeing:
- Excellent repeatability between different batches
- Linearity over the entire operating range
- Resistance to cross-contamination
- Ease of product changeover with CIP/SIP procedures
Management of excipients and additives
Nova Rotors volumetric pumps effectively handle:
- High-viscosity polymers for solid pharmaceutical forms
- Stable emulsions for topical preparations
- Saline solutions for injectable products
- Organic solvents for synthesis processes
Sterile applications
For applications requiring absolute sterility, Nova Rotors offers:
- Autoclave sterilizable pumps at 134°C
- Integrated CIP/SIP systems
- Single-use sterile connections
- Sterility validation according to pharmaceutical regulations
Regulatory compliance and certifications
Nova Rotors guarantees full compliance with the most stringent international pharmaceutical sector regulations.
Quality certifications
The company maintains the following certifications for the pharmaceutical sector:
- ISO 9001:2015 for quality management systems
- ATEX for applications in explosive atmospheres
- CE Marking for European conformity
- 3A sanitary standard
Regulatory support
Nova Rotors provides complete support for:
- Preparation of regulatory dossiers
- Validation documentation
- Qualified supplier audits
- Personnel training on GMP regulations
Specialized assistance for industrial pumps
Nova Rotors industrial pump assistance for the pharmaceutical sector goes beyond traditional maintenance, offering specialized services that guarantee operational continuity and regulatory compliance.
Predictive maintenance
We use advanced technologies for predictive maintenance:
- Vibration analysis
- Infrared thermography for anomaly detection
- Remote monitoring through industrial IoT
Periodic qualification services
To maintain validation over time, Nova Rotors keeps updated:
- Annual requalifications according to GMP protocols
- Certified calibration of all instruments
- Technical documentation updates
- Continuous personnel training
24/7 technical support
The Nova Rotors expert team guarantees:
- Emergency intervention in northern and central Italy
- Remote diagnosis through digital systems
- Original spare parts always available
- Temporary backup during scheduled maintenance
Integration with process control systems
Nova Rotors pumps integrate perfectly with modern pharmaceutical control systems.
Compatibility with MES and ERP PLM
Nova Rotors systems communicate natively with:
- Manufacturing Execution Systems (MES)
- Enterprise Resource Planning (ERP)
- Product lifecycle management (PLM)
- Process Control Systems (PCS)
Customization for specific processes
Every pharmaceutical process has unique requirements. Nova Rotors offers completely customized solutions.
Custom design
The Nova Rotors engineering team develops specific solutions for:
- Small-scale batch processes for research and development
- Continuous production for high-volume pharmaceuticals
- Sterile processes for injectable products
- Toxic solvent handling with special containment
Design validation
Every customization includes:
- FEM analysis for structural optimization
- CFD simulations for hydrodynamic validation
- Accelerated durability tests
- Performance validation under extreme conditions
- Possibility to test the products to be pumped at our facilities before purchasing the pumps
Optimize your pharmaceutical processes with Nova Rotors: contact our specialists for personalized technical consultation. With over 30 years of experience and cutting-edge technologies, we are the ideal partner for your precision dosing challenges. From design to specialized maintenance, Nova Rotors guarantees complete solutions compliant with the most stringent pharmaceutical sector regulations.
Request a technical evaluation for your pharmaceutical applications